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PMIC CHLORIDE

5-Methyl-3-phenylisoxazole-4-carbonyl chloride

CAS: 16883-16-2

Molecular Formula: C11H8ClNO2

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PMIC CHLORIDE - Names and Identifiers

Name 5-Methyl-3-phenylisoxazole-4-carbonyl chloride
Synonyms PMIC Chloride
PMIC CHLORIDE
5-methyl-3-phenyl-4-isoxazolecarbonylchlorid
5-METHYL-3-PHENYL-4-CHLOROCARBONYL ISOXAZOLE
5-Methyl-3-phenyl-4-isoxazolecarbonylchloride
5-Methyl-3-phenylisoxazole-4-carbonyl chloride
3-PHENYL-5-METHYLISOXAZOLE-4-CARBONYL CHLORIDE
5-METHYL-3-PHENYLISOXAZOLE-4-CARBONYL CHLORIDE
5-methyl-3-phenyl-1,2-oxazole-4-carbonylchloride
5-Methyl-3-phenyl-1,2-oxazole-4-carbonyl chloride
5-Methyl-3-Phenyl-Isoxazol-4-Carboxylicacid Chloride
CAS 16883-16-2
EINECS 240-915-4
InChI InChI=1/C11H8ClNO2/c1-7-9(11(12)14)10(13-15-7)8-5-3-2-4-6-8/h2-6H,1H3

PMIC CHLORIDE - Physico-chemical Properties

Molecular FormulaC11H8ClNO2
Molar Mass221.64
Density1.27
Melting Point24 °C
Boling Point115-117 °C(Press: 3 Torr)
Flash Point>100
Water Solubility701.8mg/L at 25℃
Solubility soluble in Methanol
Vapor Presure0.007Pa at 25℃
Appearancepowder to lump
ColorWhite to Light yellow
pKa-4.78±0.50(Predicted)
Storage ConditionRoom Temprature
SensitiveMoisture Sensitive
Refractive Index1.562
MDLMFCD00052205
Physical and Chemical PropertiesCrystallization. Melting point 184 °c.
UseUsed as an intermediate of benzoxazole penicillin sodium

PMIC CHLORIDE - Risk and Safety

Risk CodesR22 - Harmful if swallowed
R34 - Causes burns
R36 - Irritating to the eyes
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S26/36/37/39/45 -
S20 - When using, do not eat or drink.
UN IDsUN3261
TSCAYes
Hazard NoteCorrosive
Hazard Class8
Packing GroupII

PMIC CHLORIDE - Reference Information

LogP1.97 at 25℃
EPA chemical information Information provided by: ofmpub.epa.gov (external link)
use intermediate of penicillin sodium.
Used as an intermediate of penicillin sodium
Production method Use benzaldehyde and hydroxylamine hydrochloride to oxime under alkaline conditions to generate benzoxime, and then chlorinate with chlorine to obtain benzoxime Chloride, the latter merges with ethyl acetoacetate ring under the action of alkali to hydrolyze the ester group to obtain 5-methyl-3-phenyl-4-isoxazolic acid, finally, the product was obtained by chlorination of phosphorus pentachloride.
Last Update:2024-04-09 02:00:07
PMIC CHLORIDE
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CAS: 16883-16-2
Tel: +86-18821248368
Email: Int06@meryer.com
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CAS: 16883-16-2
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View History
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